A list of refereed publications in this calender year is provided here. Please press on the “Download” link to download the publication in pdf format (available when publication is finalized)

 

Title Status
J. Valencia-Serna, H.M. Aliabadi, A. Manfrin, M. Mohsani, X. Jiang, H. Uludağ. siRNA/Polymer nanoparticles to arrest growth of chronic myeloid leukemia cells in vitro and in vivo. Eur. J. Pharmaceutics and Biopharmaceutics (2018) in press.
   0 download
In press
D. Gugulothu, A. Barhoum, S.M. Afzal, B. Venkateshwarlu, H. Uludağ. Structural multifunctional nanofibers and their emerging applications. In Handbook of Nanofibers, A. Barhoum, M. Bechelany, A. Makhlouf (Eds.) Springer, Germany (2018) in press.
   0 download
In press
H. Kaur, A.G. Siraki, M. Sharma, H. Uludağ, D.N. Dederich, P. Flood, T. El-Bialy. Reactive oxygen species (ROS) mediate therapeutic ultrasound induced Mitogen Activated Protein Kinases activation in C28/I2 chondrocytes. Ultrasound in Medicine and Biology (2018) in press.
   0 download
In press
R. Rasouli, A. Barhoum, H. Uludağ. A review of nanostructured materials for dental implants: coating, pattering and surface functionalization for improved performance. Biomaterials Science (2018) 29: 1312-1338.
   3 downloads
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D.S. Bilecen, J.C. Rodriguez-Cabello, H. Uludağ, V. Hasirci. Development of PEI-RANK siRNA complex loaded PLGA nanocapsules for the treatment of osteoporosis. Tissue Engineering (2018), in press.
   0 download
In press
M.B. Parmar, D.N. Meenakshi Sundaram, H. Kaur,, Remant Bahadur KC, R. Maranchuk, H.M. Aliabadi, J.C. Hugh, R. Löbenberg, H. Uludağ. Combinational siRNA delivery using hyaluronic acid modified amphiphilic polyplexes against cell cycle and phosphatase proteins to inhibit growth and migration of triple-negative breast cancer cells. Acta Biomaterialia (2018) 66: 294-309.
   34 downloads
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D. Meneksedag-Erol, T. Tang, H. Uludağ. Mechanistic insights into the role of glycosaminoglycans in nucleic acid delivery: a molecular dynamics simulation study. Biomaterials (2018) 156: 107-120.
   17 downloads
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B. Thapa, Remant Bahadur KC, H. Uludağ. Complementary therapeutic targets to enhance TRAIL-induced apoptosis in breast cancer cells. International J. Cancer (2018) 142: 597-606.
   18 downloads
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Title Status
D.S. Bilecen, J.C. Rodriguez-Cabello, H. Uludağ, V. Hasirci. Construction of a PLGA based, targeted siRNA delivery system to be used in the treatment of osteoporosis. J. Biomaterials Science Polymer Ed. (2017) 28: 1859-1873.
   125 downloads
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H. Kaur, A.G. Siraki, H. Uludağ, D.N. Dederich, P. Flood, T. El-Bialy. Role of reactive oxygen species during low intensity pulsed ultrasound application in MC-3T3 E1 pre-osteoblast cell culture. Ultrasound in Medicine and Biology (2017) 43: 2699-2712.
   92 downloads
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Remant Bahadur KC, B. Thapa, J. Valencia-Serna, H.M. Aliabadi, H. Uludağ. Nucleic acid combinations: a new frontier for cancer treatment. J. Controlled Release (2017) 256:153-169.
   212 downloads
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D. N. Meenakshi Sundaram, C. Kucharski, M.B. Parmar, Remant Bahadur KC, H. Uludağ. Targeting Integrin-β1 to reduce attachment and migration of breast cancer cells. Macromol. Biosci. (2017) 17: 1600430.
   120 downloads
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D. Pezzoli, E. Tsekoura, Remant K.C., G. Candiani, D. Mantovani, H. Uludağ, Hydrophobe-substituted PEI derivatives: boosting transfection of primary vascular cells. Science China Materials (2017) 60: 529–542.
   216 downloads
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E.K. Tsekoura, Remant Bahadur KC, H. Uludağ. Biomaterials to facilitate delivery of RNA agents in bone regeneration and repair. ACS Biomaterials Science and Engineering (2017) 3: 1195–1206.
   187 downloads
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H. Kaur, H. Uludağ, D.N. Dederich, T. El-Bialy. Effect of increasing Low Intensity Pulsed Ultrasound and functional appliance on mandibular condyle in growing rats. J. Ultrasound in Medicine (2017) 36:109-120.
   115 downloads
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Title Status
H.M. Aliabadi, P. Mahdipoor, M. Bisoffia, J.C. Hugh, H. Uludağ. Single and combinational siRNA therapy of cancer cells: probing changes in targeted and non-targeted mediators after siRNA treatment. Molecular Pharmaceutics (2016) 13: 4116-4128.
   438 downloads
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M.B. Parmar, B.E. Arteaga Ballesteros, T. Fu, Remant Bahadur KC, H.M. Aliabadi, J.C. Hugh, R. Löbenberg, H. Uludağ. Multiple siRNA delivery against cell cycle and anti-apoptosis proteins using lipid-substituted polyethylenimine in triple-negative breast cancer and non-malignant cells. J. Biomed. Mat. Res. A (2016) 104: 3031-3044.
   211 downloads
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K. Utsuno, N. Jouna, E. Tanaka, Y. Kojima, H. Uludağ. Low molecular weight branched PEI binding to linear DNA. Chem. Pharmaceut. Bull (2016) 64: 1484–1491.
   280 downloads
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S.M. Garg, A. Falamarzian, M.R. Vakili, H.M. Aliabadi, H. Uludağ, A. Lavasanifar. Polymeric micelles for MCL-1 gene silencing in breast tumors following systemic administration. Nanomedicine (2016) 11: 2319-2339.
   360 downloads
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T.A. Aldosary, H. Uludağ, M. Doschak, T. El-Bialy. Osteogenic differentiation of human umbilical cord peri-vascular 1 cells using Low Intensity Pulsed Ultrasound. Journal of Stem Cell Research & Therapy (2016) 6: 335.
   296 downloads
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H. Uludağ, B. Landry, J. Valencia-Serna, Remant-Bahadur K.C. and D. Meneksedağ-Erol. Current attempts to implement siRNA-Based RNAi in leukemia models. Drug Discovery Today (2016) 21: 1412-1420.
   225 downloads
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P. Zhu, H.M. Aliabadi, H. Uludağ, J. Han. Identification of potential drug targets in breast cancer signaling pathway using stochastic logical models. Scientific Reports (2016) 6:23078.
   386 downloads
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J. Valencia-Serna, P. Chevallier, G. Laroche, H. Uludağ. Fibronectin-modified surfaces for evaluating the influence of cell adhesion on sensitivity of leukemic cells to siRNA nanoparticles. Nanomedicines (2016) in press.
   283 downloads
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B. Thapa, S. Plianwong, Remant Bahadur KC, B. Rutherford, H. Uludağ. Small hydrophobe substitution on polyethylenimine for plasmid DNA delivery: Optimal substitution is critical for effective delivery. Acta Biomaterialia (2016) 33: 213-224.
   345 downloads
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B. Landry, H. Gül-Uludağ, S. Plianwong, C. Kucharski, Z. Zak, M.B. Parmar, O. Kutsch, H. Jiang, J. Brandwein, H. Uludağ. Targeting CXCR4/SDF-1 axis by lipopolymer complexes of siRNA in acute myeloid leukemia. J Control Release (2016) 224: 8-21.
   389 downloads
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Title Status
D. Meneksedag-Erol, Remant Bahadur KC, T. Tang, H. Uludağ. A delicate balance when substituting a small hydrophobe onto low molecular weight polyethylenimine to improve its nucleic acid delivery efficiency. ACS Applied Materials & Interfaces (2015) 7: 24822-24832.
   313 downloads
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T.A. Aldosary, H. Uludağ, M. Doschak, T. El-Bialy. Effect of ultrasound on human umbilical cord peri-vascular cells. J. Biomedical Engineering & Informatics (2015) 1: 70-81.
   239 downloads
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H.M. Aliabadi, P. Mahdipoor, C. Kucharski, N. Chan, H. Uludağ. Effect of siRNA pre-exposure on subsequent response to siRNA therapy. Pharm. Res. (2015) 32: 3813-3826.
   269 downloads
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B. Landry, J. Valencia-Serna, H. Gul-Uludağ, X. Jiang, A. Janowska-Wieczorek, J. Brandwein, H. Uludağ. Progress in RNAi mediated molecular therapy of acute and chronic myeloid leukemia. Molecular Therapy Nucleic Acids (2015) 4: e240.
   349 downloads
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Remant Bahadur KC, C. Kucharski, H. Uludağ. Additive nanocomplexes of cationic lipopolymers for improved non-viral gene delivery to mesenchymal stem cells. J. Mat. Chem. (2015) 3: 3972-3982.
   310 downloads
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D. Meneksedağ-Erol, T. Tian, H. Uludağ. Probing the effect of miRNA on siRNA – PEI polyplexes. J. Phys. Chem. B (2015) 119: 5475-5486.
   435 downloads
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M.B. Parmar, H.M. Aliabadi, P. Mahdipoor, C. Kucharski, R. Maranchuk, J.C. Hugh, H. Uludağ. Targeting cell cycle proteins in breast cancer cells with siRNA by using lipid-substituted polyethylenimines. Frontiers in Biotechnology & Bioengineering (2015) 3:14.
   331 downloads
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M. Parmar, H. Uludag. Cell Cycle Regulation as a Target for RNAi Mediated Cancer Therapy. In Nanomedicines: Design, Delivery and Detection, M. Braddock (Ed.) (2015) in press.
   1 download
In press
Remant K.C., H. Uludag. PEI and Its Derivatives in Gene Delivery. In Polymers and Nanomaterials in Gene Delivery. R. Narain (Ed). Woodhead Publishing Limited, Cambridge, UK (2015) in press.
   1 download
In press
H.M. Aliabadi, H. Uludag. Nanoparticle Carriers to Overcome Biological Barriers Barriers to siRNA Delivery. In Nanomedicines: Design, Delivery and Detection, M. Braddock (Ed.) (2015) in press.
   1 download
In press

Title Status
A. Falamarzian, H.M. Aliabadi, 0. Molavi, J.M. Seubert, R. Lai, H. Uludag, A. Lavasanifar. Effective down-regulation of signal transducer and activator of transcription 3 (STAT3) by polyplexes of siRNA and lipid-substituted polyethyleneimine for sensitization of breast tumor cells to conventional chemotherapy. J. Biomed. Mat. Res. A. (2014) 102: 3216-3228.
   250 downloads
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L Rose, C. Kucharski, P. Mandipoor, H. Uludag. Pharmacokinetics and transgene expression by polytheylenimine-based pDNA complexes after in vivo gene delivery. Biomaterials Science (2014) 2: 833-842.
   303 downloads
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H. Kaur, H. Uludag, T. El-Bialy. Effect of non-viral plasmid delivered basic Fibroblast Growth Factor and Low Intensity Pulsed Ultrasound on mandibular condylar growth: a preliminary study. BioMed Research Int. (2014) 2014:426710.
   226 downloads
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H. Gul-Uludag, J. Valencia-Serna, C. Kucharski, L.A. Marquez-Curtis, X. Jiang, L. Larratt, A. Janowska-Wieczorek, H. Uludag. Nanoparticle-mediated silencing of CD44 receptor in CD34+ acute myeloid leukemia blasts. Leukemia Research (2014) in press.
   272 downloads
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B. Sahin, J. Fife, M. Parmar, J. Valencia-Serna, H. Gul-Uluda, X. Jiang, M. Weinfeld A. Lavasanifar, H. Uludag. Polymeric carriers for siRNA delivery in cutaneous T-cell lymphoma cells. Biomaterials (2014) 35: 9382-9394.
   246 downloads
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D. Meneksedag-Erol, T. Tang, H. Uludag. Molecular modelling of polynucleotide complexes. Biomaterials (2014) 35: 7068-7076.
   325 downloads
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H. Uludag. Grand Challanges in Biomaterials Science. Frontiers in Bioengineering and Biotechnology (2014) 2: 43.
   221 downloads
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J. Valencia-Serna, B. Landry, X. Jiang, H. Uludag. Potential of siRNA Therapy in Chronic Myeloid Leukemia. In Intracellular Drug Delivery: Fundamentals and Applications, Volume II, A. Prokop, Y. Iwasaki, A. Harada (Eds) Springer (2014), pp 435-473.
   266 downloads
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D. Meneksedag-Erol, C. Sun, T. Tang, H. Uludag. Molecular Dynamics Simulations of Polyplexes and Lipoplexes Employed in Gene Delivery. In Intracellular Drug Delivery: Fundamentals and Applications, Volume II, A. Prokop, Y. Iwasaki, A. Harada (Eds) Springer (2014), pp 277-312.
   292 downloads
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Title Status
M. Abbasi, A. Lavasanifar, H. Uludag. Recent attempts at RNAi based downregulation of P-glycoprotein in reversing multidrug resistance in cancer. Medicinal Research Reviews (2013) 33: 33-53.
   343 downloads
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C. Sun, T. Tang, H. Uludag. A molecular dynamics simulation study on the effect of lipid substitution on polyethylenimine mediated siRNA complexation. Biomaterials (2013) 34: 2822-2833.
   231 downloads
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L Rose, R. Fitzsimmons, P. Lee, R. Krawetz, D.E. Rancourt, H. Uludag. Effect of bFGF in mouse embryonic stem cell culture and osteogenic differentiation. Journal of Tissue Engineering & Regenerative Medicine (2013) 7: 371-382.
   219 downloads
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J. Valencia-Serna, H. Gul-Uludag, P. Mandipoor, J. Jiang, H. Uludag. Investigating siRNA delivery to chronic myeloid leukemia K562 cells with lipophilic polymers for therapeutic BCR-ABL down-regulation. Journal of Controlled Release (2013) 172: 495-503.
   278 downloads
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B. Dube, L. Rose, K. Sawant, H. Uludag. Cholic acid modified 2 kDa PEI as efficient transfection agents. Biotechnology Progress (2013) 29: 1337-1341.
   213 downloads
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Y. Wang, N.Z. Mostafa, C.Y.M. Hsu, L Rose, C. Kucharki, J. Yan, H. Jiang, H. Uludag. Modification of human BMSC with nanoparticles of polymeric biomaterials and plasmid DNA for BMP-2 secretion. Journal of Surgical Research (2013) 183: 8-17.
   258 downloads
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H.M. Aliabadi, P. Mandipoor, H. Uludag. Polymeric delivery of siRNA for dual silencing of Mcl-1 and P-glycoprotein and apoptosis induction in drug-resistant human breast cancer cells. Cancer Gene Therapy (2013) 20: 169-177.
   268 downloads
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L Rose, H.M. Aliabadi, H. Uludag. Gelatin coating to stabilize the transfection ability of nucleic acid polyplexes. Acta Biomaterialia (2013) 7: 7429-7438.
   240 downloads
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L Rose, H. Uludag. Realizing the potential of gene-based molecular therapies in bone repair.Journal of Bone & Mineral Research (2013) 28: 2245-2262.
   277 downloads
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H.M. Aliabadi, P. Mandipoor, R. Marenchuk, J. Hugh, H. Uludag. Combinational siRNA therapy in drug-sensitive and drug-resistant breast cancer cells. Journal of Controlled Release (2013) 172: 219-228.
   251 downloads
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Title Status
C. Sun, T. Tang, H. Uludag. Probing the effects of lipid substitution on polycation mediated DNA aggregation: a molecular dynamics simulations study. Biomacromolecules (2012) 13: 2982-2988.
   280 downloads
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B. Landry, H.M. Aliabadi, A. Samuel, H. Giil-Uludag, X. Jiang, 0. Kutsch, H. Uludag. Effective non-viral delivery of siRNA to acute myeloid leukemia cells with lipid-substituted polyethylenimines. PLOS One (2012) 7: e44197
   293 downloads
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C. Chen, H. Uludag, Z. Wang, A. Rezansoff, H. Jiang. Macrophages inhibit migration, metabolic activity and osteogenic differentiation of human mesenchymal stem cells in vitro. Cells, Tissue, Organs (2012) 195: 473-483.(no link to paper)
   224 downloads
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C. Chen, H. Uludag, Z. Wang, H. Jiang. Noggin suppression decreases BMP-2 induced osteogenesis of human bone marrow mesenchymal stem cells in vitro. J. Cell. Biochem. (2012) 113: 3672-3680.
   265 downloads
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C.Y.M Hsu, H. Uludag. Nucleic-acid based gene therapeutics: delivery challenges and modular design of gene carriers and expression cassettes to overcome intracellular barriers to sustained targeted expression. J. Drug Targeting (2012) 20: 301-328.
   281 downloads
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A. Falamarzian, X-B. Xiong, H. Uludag, A. Lavasanifar. Polymeric micelles for targeted siRNA delviery. J. Drug Del. Sci. Technol. (2012) 22: 43-54.
   243 downloads
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H.M. Aliabadi, B. Landry, C. Sun, T. Tang, H. Uludag. Supramolecular in functional siRNA delivery: where do we stand? Biomaterials (2012) 33: 2546-69.
   283 downloads
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C. Sun, T. Tang, H. Uludag. Molecular dynamics simulations of complexation of DNA with 2 kDa PEI reveals profound effects of architecture on complexation. J. Phys. Chem B (2012) 116: 2405-2413.
   232 downloads
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C.Y.M. Hsu, H. Uludag. A simple and rapid non-viral approach to efficiently transfect primary tissue derived cells using polyethylenimine. Nature Protocols (2012) 7: 935-945.
   294 downloads
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R.E.B. Fitzsimmons, H. Uludag. Specific effects of PEGylation on gene delivery efficacy of PEI: interplay between PEG substitution and N/P ratio. Acta Biomaterilia (2012) 8: 3941-3955.
   278 downloads
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H. Yogasundaram, M.S. Bahniuk, HD. Singh, H.M. Aliabadi, H. Uludag, L.D Unsworth. BSA nanoparticles for siRNA delivery: effect of nanoparticle coating on plasma protein adsorption and in vitro siRNA delivery. Int. J. Biomat. (2012) ID 584060.
   262 downloads
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H.M. Aliabadi, B. Landry, C.Y.M Hsu P. Mandipoor, H. Uludag. Down-regulation of Breast Cancer Resistance Protein (BCRP) by siRNA delivery using lipid-substituted aliphatic polymers. Eur. J. Pharmaceutics and Biopharmaceutics (2012) 81: 33-42.
   280 downloads
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G. Wang, N.Z. Mostafa, V. Incani, C. Kucharski, H. Uludag. Bisphosphonate-decorated lipid nanoparticles designed as drug carriers for bone diseases. J. Biomed. Mat. Res. (2012) 100A: 684-695.
   261 downloads
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C.Y.M. Hsu, H. Uludag. Cellular uptake pathways of lipid-modified cationic polymers in gene delivery to primary cells. Biomaterials (2012) 33: 7834-7848.
   248 downloads
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L Rose, C. Kucharski, H. Uludag. Protein expression following non-viral delivery of plasmid DNA coding for bFGF and BMP-2 in a rat ectopic model. Biomaterials (2012) 33: 3363-3374.
   271 downloads
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N.Z. Mostafa, R. Fitzsimmons, P.W. Major, A. Adesida, N. Jomha, H. Jiang, H. Uludag Osteogenic differentiation of human mesenchymal stem cells with dexamethasone, vitamin D3, basic Fibroblast Growth Factor and Bone Morphogenetic Protein-2. Connective Tissue Research (2012) 53: 117-131.
   301 downloads
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Title Status
H.M. Aliabadi, B. Landry, P. Mandipoor, H. Uludag. Induction of apoptosis by surviving silencing through siRNA delivery in a human breast cancer cell line. Molecular Pharmaceutics (2011) 8: 1821-1830.
   274 downloads
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D. Zhang, F. Chu, Y. Yang, L. Xia, D. Zeng, X. Zhang, H. Uludag, Y. Q_ian, X. Jiang. Orthodontic tooth movement in alveolar cleft repaired with a tissue engineering bone: an experimental study in dogs. Tissue Engineering (2011) 17: 1313-1325.
   309 downloads
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L. Zhi, C. Chen, X. Pang, H. Uludag, H. Jiang. Synergistic effect of rhBMP-7 and osteogenic differentiation medium on human bone marrow-derived mesenchymal stem sells in vitro. Int. Orthopeadics (2011) 35:1889-1895.
   202 downloads
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M. Abbasi, H.M. Aliabadi, E.H. Moase, A. Lavasanifar, K. Kaur, R. Lai, C. Doillon, H. Uludag. siRNA mediated down-regulation of P-glycoprotein in a xenograft tumor model in NOD-SCID mice. Pharm. Res. (2011) 28: 2516-2529.
   322 downloads
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G. Wang, M.E. Babadagli, H. Uludag. Bisphosphonate-derivatized liposomes to control drug release from collagen/hydroxyapatite scaffolds. Mol. Pharmaceutics (2011) 8:1025-1034.
   351 downloads
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N.Z. Mostafa, H. Uludag, M. Varkey, D.N. Dederich, M.R. Doschak, T.H. El-Bialy. In vitro osteogenic induction of human gingival fibroblasts for bone regeneration. Open Dental Journal (2011) 5:139-145.
   308 downloads
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A. Alshamsan, S. Hamdy, I. Samuel, A. Haddadi, A.O.S. El-Kadi, A. Lavasanifar, H. Uludag. STAT3 knockdown in BIG melanoma by siRNA lipopolyplexes induces bystander immune response in vitro and in vivo. Translational Oncology (2011) 4: 178-188.
   268 downloads
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H.M. Aliabadi, B. Landry, R. Bahadur K.C., A. Neamnark, 0. Suwantong, H. Uluda. Impact of lipid-substitution on assembly and delivery of siRNA by cationic polymers. Macromol. Biosci. (2011) 11: 662-672.
   270 downloads
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C. Hsu, M. Hendzel, H. Uludag. Improved transfection efficiency of an aliphatic lipid substituted 2 kDa polyethylenimine is attributed to enhanced nuclear association and uptake in rat bone marrow stromal cells. 1. Gene Med. (2011) 13: 46-59.
   203 downloads
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C. Sun, J.E. Cuervo, T. Tang, H. Uludag. Molecular dynamics simulations of DNA/PEI complexes: Effect of PEI branching and protonation ratio. Biophys. l (2011) 100: 2754-2763.
   234 downloads
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Remant K.C., H. Uludag. A comparative evaluation of disulfide-linked and hydrophobically-modified PEI for plasmid delivery. I. Biomat. Sci. Poly. Ed. (2011) 22: 873-892.
   279 downloads
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Remant Bahadur K.C., B. Landry, H.M. Aliabadi, et al. Lipid-substitution on low molecular weight (0.6 – 2.0 kDa) PEI leads to higher zeta-potential with plasmid DNA and enhances transgene expression. Acta Biomaterialia (2011) 7: 2209-2217.
   210 downloads
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C. Sun, T. Tang, H. Uludag. Molecular dynamics simulations of PEI mediated DNA aggregation. Biomacromolecules (2011) 12: 3698-3707.
   371 downloads
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H.M. Aliabadi, B. Landry, P. Mahdipoor, H. Uludag. Induction of apoptosis by surviving silencing through siRNA delivery in a human breast cancer cell line. Molecular Pharmaceutics (2011) 8: 1821-1830.


C. Sun, T. Tang, H. Uludag. Molecular dynamics simulations of PEI mediated DNA aggregation. Biomacromolecules (2011) 12: 3698-3707.


N.Z. Mostafa, H. Uluda, M. Varkey, D.N. Dederich, M.R. Doschak, T.H. El-Bialy. In vitro osteogenic induction of human gingival fibroblasts for bone regeneration. Open Dental Journal (2011) 5:139-145.


G. Wang, M.E. Babadali, H. Uludag. Bisphosphonate-derivatized liposomes to control drug release from collagen/hydroxyapatite scaffolds. Mol. Pharmaceutics (2011) 8: 1025-1034.


M. Abbasi, H.M. Aliabadi, E.H. Moase, A. Lavasanifar, K. Kaur, R. Lai, C. Doillon, H. Uludag. siRNA mediated down-regulation of P-glycoprotein in a xenograft tumor model in NOD-SCID mice. Pharmaceutical Research (2011) 28: 2516-2529.


C. Sun, J.E. Cuervo, T. Tang, H. Uludag. Molecular dynamics simulations of DNA/PEI complexes: Effect of PEI branching and protonation ratio. Biophys. J (2011) 100: 2754-2763.


A. Alshamsan, S. Hamdy, J. Samuel, A. Haddadi, A.O.S. El-Kadi, A. Lavasanifar, H. Uludag. STAT3 knockdown in B16 melanoma by siRNA lipopolyplexes induces bystander immune response in vitro and in vivo. Translational Oncology (2011) 4: 178-188.


Remant Bahadur K.C., B. Landry, H.M. Aliabadi, A. Lavasanifar, H. Uluda, Lipid-substitution on low molecular weight (0.6 – 2.0 kDa) polyethylenimine leads to higher zeta-potential with plasmid DNA and enhances transgene expression. Acta Biomaterialia (2011) 7: 2209-2217.


D. Zhang, F. Chu, Y. Yang, L. Xia, D. Zeng, X. Zhang, H. Uludag, Y. Qian, X. Jiang. Orthodontic tooth movement in alveolar cleft repaired with a tissue engineering bone: an experimental study in dogs. Tissue Engineering (2011) 17: 1313-1325.


H.M. Aliabadi, B. Landry, R. Bahadur K.C., A. Neamnark, O. Suwantong, H. Uluda. Impact of lipid-substitution on assembly and delivery of siRNA by cationic polymers. Macromol. Biosci. (2011) 11: 662-672.


C. Hsu, M. Hendzel, H. Uludag. Improved transfection efficiency of an aliphatic lipid substituted 2 kDa polyethylenimine is attributed to enhanced nuclear association and uptake in rat bone marrow stromal cells. J. Gene Med. (2011) 13: 46-59.


Remant K.C., H. Uludag. A comparative evaluation of disulfide-linked and hydrophobically-modified PEI for plasmid delivery. J. Biomat. Sci. Poly. Ed. (2011) 22: 873-892.


A. Alshamsan, A. Haddadi, S. Hamdy, J. Samuel, A.O.S. El-Kadi, H. Uluda, A. Lavasanifar. STAT3 silencing in dendritic cells by siRNA siRNA polyplexes encapsulated in PLGA nanoparticles for the modulation of anticancer immune response. Molecular Pharmaceutics (2010) 7: 1643-1654.


C.E. Taghavi, K-B. Lee, W. He, G. Keorochana, S.S. Murray, E.J. Brochmann, H. Uluda, K. Behnam, J.C. Wang. Bone morphogenetic protein binding peptide mechanism and enhancement of Osteogenic Protein-1 induced bone healing. Spine (2010) 35: 2049-2056.


H.D Singh, G. Wang, H. Uluda, L.D. Unsworth. Poly-L-Lysine coated albumin nanoparticles: stability, mechanism for increasing in vitro enzymatic resilience, and siRNA release characteristics. Acta Biomaterialia (2010) 6: 4277–4284.


K.H. Bhandari, M. Newa, H. Uluda, M.R. Doschak. Synthesis, characterization and in vitro evaluation of a bone targeting delivery system for salmon calcitonin. Int J Pharmaceut (2010) 394: 26-34.


K. Utsuno, H. Uluda. Thermodynamics of PEI-DNA binding and DNA condensation. Biophys. J (2010) 99: 201-207.


X-B. Xiong, H. Uluda, A. Lavasanifar. Virus-mimetic polymeric micelles for targeted siRNA delivery to human cancer cells. Biomaterials (2010) 31: 5886-5893.


S. Zhang, C. Kucharski, M.R. Doschak, W. Sebald, H. Uluda. Polyethylenimine-PEG coated albumin nanoparticles for BMP-2 Delivery. Biomaterials (2010) 31: 952-63.


T. El-Bialy, H. Uludag, N. Jomha, S. Badylak. In vivo ultrasound assisted tissue engineered mandibular condyle: A pilot study in rabbits. Tissue Engineering (2010) 16: 1315-1323.


M. Abbasi, A. Lavasanifar, L. Berthiaume, M. Weinfeld, H. Uluda. Cationic polymer mediated siRNA delivery for P-glycoprotein (P-gp) down-regulation in tumor cells. Cancer (2010) 116: 5544-5554.


G. Wang, C. Kucharski, X. Lin, H. Uluda. Bisphosphonate-coated BSA nanoparticles lacks bone targeting after systemic administration. J. Drug Target. (2010) 18: 611-626.


S. Wang, Z. Zhang, L. Xia, J. Zhao, X. Sun, X. Zhang, D. Ye, H. Uluda, X. Jiang. Systematic evaluation of a tissue-engineered bone for maxillary sinus augmentation in large animal canine model. Bone (2010) 46: 91-100.


A. Alshamsan, J. Samuel, H. Uluda, A.O.S. El-Kadi, A. Lavasanifar. The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine. Biomaterials (2010) 31: 1420-1428.


V. Incani, A. Lavasanifar A, H. Uluda. Hydrophobic modification of cationic polymers on route to superior gene carriers. Soft Matter (2010) 6: 2124–2138.


A. Naemnark, O. Suwantang, Remant Bahadur K.C., Charlie Y.M. Hsu, P. Supaphol, H. Uluda. Aliphatic lipid substitution on 2 kDa-polyethylenimine improves plasmid delivery and transgene expression. Mol. Pharmaceut. (2009) 6: 1798-1815.


S. Zhang, M. Doschak, H. Uluda. Pharmacokinetics and bone formation by BMP-2 entrapped in polyethylenimine-coated albumin nanoparticles. Biomaterials (2009) 30: 5143-5155.


N.Z. Mostafa, H. Uluda, D.N. Dederich, M. Doschak, T. El-Bialy. Anabolic effects of low intensity pulsed ultrasound on gingival fibroblasts. Arch. Oral Biol. (2009) 54: 743-748.


V. Incani, X. Lin, A. Lavasanifar, H. Uluda. Relationship between the extent of lipid substitution on Poly(L-Lysine) and DNA delivery efficiency. Appl. Mat. Interf. (2009) 1: 841-848.


B.A. Clements, C.Y.M. Hsu, C. Kucharski, X. Lin, L. Rose, H. Uluda. Non-viral delivery of basic Fibroblast Growth Factor (bFGF) gene to bone marrow stromal cells. Clin. Orthop. Rel. Res. (2009) 467: 3129-3137.


R.B. Jalili, F. Forouzandeh, A. Moeenrezakhanlou, G.R. Rayat, R.V. Rajotte, H. Uluda, A. Ghahary. Mouse pancreatic islets are resistant to Indoleamine 2,3 Dioxygenase-induced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function. Am. J. Pathol. (2009) 174: 196-205.


M.R. Doschak, C.M Kucharski, J.E.I. Wright, R.F. Zernicke, H. Uluda, Improved bone delivery of osteoprotegerin by bisphosphonate conjugation in a rat osteoarthritis model. Mol. Pharmaceut. (2009) 6: 634-640.


A. Alshamsan, A. Haddadi, V. Incani, J. Samuel, A. Lavasanifar, H. Uluda. Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine.. Mol. Pharmaceut. (2009) 6: 121-133.


X.B. Xiong, H. Uluda, A. Lavasanifar. Biodegradable amphiphilic poly(ethylene oxide)-block-polyesters with grafted polyamines as supramolecular nanocarriers for efficient siRNA delivery. Biomaterials (2009) 30: 242-253.


S. Zhang, H. UludaG, Nanoparticulate systems for growth factor delivery. Pharm. Res. (2009) 26: 1561-1580.


G. Wang, K. Siggers, S. Zhang, H. Jiang, Z. Xu, R.F. Zernicke, J. Matyas, H. Uluda. Preparation of BMP-2 containing bovine serum albumin (BSA) nanoparticles stabilized by polymer coating. Pharm. Res. (2008) 25: 2896-2909.


X.-B. Xiong, A. Mahmud, H. Uludag, A. Lavasanifar. Multifunctional polymeric micelles for enhanced intracellular delivery of doxorubicin to metastatic cancer cells. Pharm. Res. (2008) 25: 2555-2566.


W.T Ang, C. Yu, J. Chen, T. El-Bialy, M. Doschak, H. Uludag, Y. Tsui. System-on-chip ultrasonic transducer for dental tissue formation and stem cell growth and differentiation. Proc. IEEE Symposium on Circuits and Systems (2008) 1818-1821.


S. Zhang, G. Wang, X. Lin, H. Jennissen, M. Chatzinikolaidou, M. Laub, H. Uludag. Polyethylenimine-coated albumin nanoparticles for BMP-2 Delivery. Biotech. Prog. (2008) 24: 945-956.


M. Abbasi, H. Uludag, C. Hsu, V. Incani, A. Jeffery. Further investigation of lipid-substituted poly(L-Lysine) polymers for transfection of human CRL fibroblasts. Biomacromol. (2008) 9, 1618-1630.


C. Hsu, H. Uludag. Effect of size and topology of DNA molecules on intracellular delivery with non-viral gene carriers. BMC Biotech. (2008) 8: 23.


B.A. Clements, V. Incani, C. Kucharski, B. Ritchie, A. Lavasanifar, H. Uludag. A comparative evaluation of poly-L-lysine-palmitic acid and LipofectamineTM 2000 for plasmid delivery to bone marrow stromal cells. Biomat. (2007) 28: 4693-4704.


S. Zhang, J.E.I. Wright, N. Ozber, H. Uludag. Interactions of cationic polymers and their bisphosphonate derivatives with hydroxyapatite. Macromol. Biosci. (2007) 7: 656-670.


L.-L. Farrell, J. Pepin, C. Kucharski, X. Lin, Z. Xu, H. Uludag. A comparison of the effectiveness of cationic polymers poly-L-lysine (PLL) and polyethyleneimine (PEI) for non-viral delivery of plasmid DNA to bone marrow stromal cells. Eur. J. Pharmaceut. Biopharmaceut. (2007) 65: 388-397.


X.-B. Xiong, A. Mahmud, H. Uludag, A. Lavasanifar. Conjugation of arginine-glycine-aspartic acid peptides to poly(ethylene-oxide)-b-poly(-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells. Biomacromol. (2007) 8: 874-884.


M. Abbasi, H. Uludag, V. Incani, C. Olson, X. Lin, D. Rutkowski, A. Ghahary, M. Weinfeld. Palmitic acid-modified poly-l-lysine for non-viral delivery of plasmid DNA to skin fibroblasts. Biomacromol. (2007) 8: 1059-1063.


M. Varkey, C. Kucharski, M.R. Doschak, S.R. Winn, E.J. Brochmann, S. Murray, J.R. Matyas, R.F. Zernicke, H. Uludag. Osteogenic response of bone marrow stromal cells form normal and ovariectomized rats treated with low dose of bFGF. Tissue Eng. (2007) 13: 809-817.


V. Incani, E. Tunis, B.A. Clements, C. Olson, C. Kucharski, A. Lavasanifar, H. Uludag. Palmitic acid substitution on cationic polymers for effective delivery of plasmid DNA to bone marrow stromal cells. J. Biomed. Mat. Res. (2007) 81: 493-504.


G. Wang, H. Uludag. Recent developments in nanoparticle-based drug delivery and targeting systems. Exp. Op. Drug Del. (2008) 5: 499-515.


S. Zhang, G. Bansal, H. Uludag. ‘Magic Bullets’ for bone diseases: progress in rational design of bone therapeutics based on bisphosphonate targeting. Chem. Soc. Rev. (2007) 36: 507-531.


X. Jiang, J. Bai, S.A. Gittens, W. Sebald, H. Uludag. Growth of Bone Marrow Stromal Cells on RGD-grafted thermoreversible (NiPAM) polymers. Mat. Sci. Eng. (2006) 37: 462-468.


B. Açan-Clemens, J. Bai, C. Kucharski, L.-L. Farrell, A. Lavasanifar, B. Ritchie, A. Ghahary, H. Uludag. RGD-conjugation to polyethyleneimine does not improve DNA delivery to bone marrow stromal cells. Biomacromol. (2006) 7: 1481-1488.


M. Varkey, C. Kucharski, T. Haque, W. Sebald, H. Uludag. In vitro osteogenic response of rat bone marrow cells to bFGF and BMP-2 treatments. Clin. Orthop. Rel. Res. (2006) 443: 113-123.


J.E.I. Wright, S.A. Gittens, G. Bansal, P.I. Kitov, D. Sindrey, C. Kucharski, H. Uludag. A comparison of mineral affinity of bisphosphonate-protein conjugates constructed with disulfide and thioether linkages. Biomaterials (2006) 27: 769-784.