A list of refereed publications in this calender year is provided here. Please press on the “Download” link to download the publication in pdf format (available when publication is finalized)

Title
Remant Bahadur K.C., B. Thapa, J. Valencia-Serna, A. Ubeda, X. Jiang, H. Uludağ. BCR-Abl silencing by siRNA: a potent approach to sensitize chronic myeloid leukemia cells to TKI therapy. Stem Cells & Development (2019) in press.
 1 file(s)  42 downloads

2019

February 1, 2019

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D.S. Bilecen, J.C. Rodriguez-Cabello, H. Uludağ, V. Hasirci. Development of PEI-RANK siRNA complex loaded PLGA nanocapsules for the treatment of osteoporosis. Tissue Engineering (2019) 25: 34-43.
 1 file(s)  22 downloads

2019

February 1, 2019

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    Title
    M.B. Parmar, Remant K.C. R. Löebenberg, H. Uludağ, Additive polyplexes to undertake siRNA therapy against CDC20 and survivin in breast cancer cells. Biomacromolecules (2018) 19: 4193−4206.
     1 file(s)  16 downloads

    2018

    February 1, 2019

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    A. Wunbeh, E. Tsekoura, C. Ayranci, H. Uludağ, Current state of fabrication processes and materials for bone tissue engineering. Acta Biomaterialia (2018) 80: 1-30.
     1 file(s)  27 downloads

    2018

    February 1, 2019

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    M. Mohseni, H. Uludağ, J.M. Brandwein. Advances in biology of acute lymphoblastic leukemia (ALL) and therapeutic implications. Am. J. Blood Research (2018) 8: 29-56.
     1 file(s)  26 downloads

    2018

    February 1, 2019

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    Y. Nademi, T. Tang, H. Uludağ. Steered molecular dynamics simulations reveal self-protecting mechanism of nanoparticles during membrane penetration. Nanoscale (2018) 10: 17671-17682.
     1 file(s)  83 downloads

    2018

    October 13, 2018

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    A. Lausch, L.C. Chong, H. Uludağ, E. Sone. Multiphasic collagen scaffolds for engineered tissue interfaces. Advanced Functional Materials (2018) 1804730.
     1 file(s)  87 downloads

    2018

    October 14, 2018

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    D. Meneksedag-Erol, J. N. Kizhakkedathu, T. Tang, H. Uludağ. Molecular dynamics simulations on nucleic acid binding polymers designed to arrest thrombosis. ACS Applied Materials Interfaces (2018) 10: 28399-28411.
     1 file(s)  90 downloads

    2018

    September 7, 2018

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    J. Valencia-Serna, H.M. Aliabadi, A. Manfrin, M. Mohsani, X. Jiang, H. Uludağ. siRNA/Polymer nanoparticles to arrest growth of chronic myeloid leukemia cells in vitro and in vivo. Eur. J. Pharmaceutics and Biopharmaceutics (2018) 130: 66-70.
     1 file(s)  102 downloads

    2018

    July 8, 2018

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    D. Gugulothu, A. Barhoum, S.M. Afzal, B. Venkateshwarlu, H. Uludağ. Structural multifunctional nanofibers and their emerging applications. In Handbook of Nanofibers, A. Barhoum, M. Bechelany, A. Makhlouf (Eds.) Springer, Germany (2018) in press.
     1 file(s)  71 downloads

    2018

    September 7, 2018

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    H. Kaur, A.G. Siraki, M. Sharma, H. Uludağ, D.N. Dederich, P. Flood, T. El-Bialy. Reactive oxygen species (ROS) mediate therapeutic ultrasound induced Mitogen Activated Protein Kinases activation in C28/I2 chondrocytes. Ultrasound in Medicine and Biology (2018) 44: 2105-2114.
     1 file(s)  58 downloads

    2018

    September 8, 2018

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    R. Rasouli, A. Barhoum, H. Uludağ. A review of nanostructured materials for dental implants: coating, pattering and surface functionalization for improved performance. Biomaterials Science (2018) 29: 1312-1338.
     1 file(s)  111 downloads

    2018

    June 13, 2018

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    M.B. Parmar, D.N. Meenakshi Sundaram, H. Kaur,, Remant Bahadur KC, R. Maranchuk, H.M. Aliabadi, J.C. Hugh, R. Löbenberg, H. Uludağ. Combinational siRNA delivery using hyaluronic acid modified amphiphilic polyplexes against cell cycle and phosphatase proteins to inhibit growth and migration of triple-negative breast cancer cells. Acta Biomaterialia (2018) 66: 294-309.
     1 file(s)  132 downloads

    2018

    April 24, 2018

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    D. Meneksedag-Erol, T. Tang, H. Uludağ. Mechanistic insights into the role of glycosaminoglycans in nucleic acid delivery: a molecular dynamics simulation study. Biomaterials (2018) 156: 107-120.
     1 file(s)  106 downloads

    2018

    April 24, 2018

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    B. Thapa, Remant Bahadur KC, H. Uludağ. Complementary therapeutic targets to enhance TRAIL-induced apoptosis in breast cancer cells. International J. Cancer (2018) 142: 597-606.
     1 file(s)  129 downloads

    2018

    April 24, 2018

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      Title
      A. Ansari, J.P. Santerre, H. Uludağ. Biomaterials for polynucleotide delivery to anchorage-independent cells. J. Materials Chemistry B (2017) 5: 7238-7261.
       1 file(s)  68 downloads

      2017

      July 9, 2018

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      D.S. Bilecen, J.C. Rodriguez-Cabello, H. Uludağ, V. Hasirci. Construction of a PLGA based, targeted siRNA delivery system to be used in the treatment of osteoporosis. J. Biomaterials Science Polymer Ed. (2017) 28: 1859-1873.
       1 file(s)  225 downloads

      2017

      September 30, 2017

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      H. Kaur, A.G. Siraki, H. Uludağ, D.N. Dederich, P. Flood, T. El-Bialy. Role of reactive oxygen species during low intensity pulsed ultrasound application in MC-3T3 E1 pre-osteoblast cell culture. Ultrasound in Medicine and Biology (2017) 43: 2699-2712.
       1 file(s)  175 downloads

      2017

      September 30, 2017

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      Remant Bahadur KC, B. Thapa, J. Valencia-Serna, H.M. Aliabadi, H. Uludağ. Nucleic acid combinations: a new frontier for cancer treatment. J. Controlled Release (2017) 256:153-169.
       1 file(s)  418 downloads

      2017

      May 17, 2017

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      D. N. Meenakshi Sundaram, C. Kucharski, M.B. Parmar, Remant Bahadur KC, H. Uludağ. Targeting Integrin-β1 to reduce attachment and migration of breast cancer cells. Macromol. Biosci. (2017) 17: 1600430.
       1 file(s)  206 downloads

      2017

      July 20, 2017

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      D. Pezzoli, E. Tsekoura, Remant K.C., G. Candiani, D. Mantovani, H. Uludağ, Hydrophobe-substituted PEI derivatives: boosting transfection of primary vascular cells. Science China Materials (2017) 60: 529–542.
       1 file(s)  336 downloads

      2017

      July 20, 2017

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      E.K. Tsekoura, Remant Bahadur KC, H. Uludağ. Biomaterials to facilitate delivery of RNA agents in bone regeneration and repair. ACS Biomaterials Science and Engineering (2017) 3: 1195–1206.
       1 file(s)  280 downloads

      2017

      July 20, 2017

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      H. Kaur, H. Uludağ, D.N. Dederich, T. El-Bialy. Effect of increasing Low Intensity Pulsed Ultrasound and functional appliance on mandibular condyle in growing rats. J. Ultrasound in Medicine (2017) 36:109-120.
       1 file(s)  190 downloads

      2017

      May 17, 2017

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        Title
        H.M. Aliabadi, P. Mahdipoor, M. Bisoffia, J.C. Hugh, H. Uludağ. Single and combinational siRNA therapy of cancer cells: probing changes in targeted and non-targeted mediators after siRNA treatment. Molecular Pharmaceutics (2016) 13: 4116-4128.
         1 file(s)  751 downloads

        2016

        December 26, 2016

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        M.B. Parmar, B.E. Arteaga Ballesteros, T. Fu, Remant Bahadur KC, H.M. Aliabadi, J.C. Hugh, R. Löbenberg, H. Uludağ. Multiple siRNA delivery against cell cycle and anti-apoptosis proteins using lipid-substituted polyethylenimine in triple-negative breast cancer and non-malignant cells. J. Biomed. Mat. Res. A (2016) 104: 3031-3044.
         1 file(s)  303 downloads

        2016

        December 26, 2016

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        K. Utsuno, N. Jouna, E. Tanaka, Y. Kojima, H. Uludağ. Low molecular weight branched PEI binding to linear DNA. Chem. Pharmaceut. Bull (2016) 64: 1484–1491.
         1 file(s)  482 downloads

        2016

        December 26, 2016

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        S.M. Garg, A. Falamarzian, M.R. Vakili, H.M. Aliabadi, H. Uludağ, A. Lavasanifar. Polymeric micelles for MCL-1 gene silencing in breast tumors following systemic administration. Nanomedicine (2016) 11: 2319-2339.
         1 file(s)  644 downloads

        2016

        December 26, 2016

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        T.A. Aldosary, H. Uludağ, M. Doschak, T. El-Bialy. Osteogenic differentiation of human umbilical cord peri-vascular 1 cells using Low Intensity Pulsed Ultrasound. Journal of Stem Cell Research & Therapy (2016) 6: 335.
         1 file(s)  478 downloads

        2016

        July 14, 2016

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        H. Uludağ, B. Landry, J. Valencia-Serna, Remant-Bahadur K.C. and D. Meneksedağ-Erol. Current attempts to implement siRNA-Based RNAi in leukemia models. Drug Discovery Today (2016) 21: 1412-1420.
         1 file(s)  314 downloads

        2016

        December 26, 2016

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        P. Zhu, H.M. Aliabadi, H. Uludağ, J. Han. Identification of potential drug targets in breast cancer signaling pathway using stochastic logical models. Scientific Reports (2016) 6:23078.
         1 file(s)  510 downloads

        2016

        July 14, 2016

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        J. Valencia-Serna, P. Chevallier, G. Laroche, H. Uludağ. Fibronectin-modified surfaces for evaluating the influence of cell adhesion on sensitivity of leukemic cells to siRNA nanoparticles. Nanomedicines (2016) in press.
         1 file(s)  379 downloads

        2016

        April 15, 2016

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        B. Thapa, S. Plianwong, Remant Bahadur KC, B. Rutherford, H. Uludağ. Small hydrophobe substitution on polyethylenimine for plasmid DNA delivery: Optimal substitution is critical for effective delivery. Acta Biomaterialia (2016) 33: 213-224.
         1 file(s)  480 downloads

        2016

        April 3, 2016

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        B. Landry, H. Gül-Uludağ, S. Plianwong, C. Kucharski, Z. Zak, M.B. Parmar, O. Kutsch, H. Jiang, J. Brandwein, H. Uludağ. Targeting CXCR4/SDF-1 axis by lipopolymer complexes of siRNA in acute myeloid leukemia. J Control Release (2016) 224: 8-21.
         1 file(s)  606 downloads

        2016

        March 4, 2016

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          Title
          D. Meneksedag-Erol, Remant Bahadur KC, T. Tang, H. Uludağ. A delicate balance when substituting a small hydrophobe onto low molecular weight polyethylenimine to improve its nucleic acid delivery efficiency. ACS Applied Materials & Interfaces (2015) 7: 24822-24832.
           1 file(s)  386 downloads

          2015

          March 4, 2016

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          T.A. Aldosary, H. Uludağ, M. Doschak, T. El-Bialy. Effect of ultrasound on human umbilical cord peri-vascular cells. J. Biomedical Engineering & Informatics (2015) 1: 70-81.
           1 file(s)  318 downloads

          2015

          September 22, 2015

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          H.M. Aliabadi, P. Mahdipoor, C. Kucharski, N. Chan, H. Uludağ. Effect of siRNA pre-exposure on subsequent response to siRNA therapy. Pharm. Res. (2015) 32: 3813-3826.
           1 file(s)  403 downloads

          2015

          March 4, 2016

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          B. Landry, J. Valencia-Serna, H. Gul-Uludağ, X. Jiang, A. Janowska-Wieczorek, J. Brandwein, H. Uludağ. Progress in RNAi mediated molecular therapy of acute and chronic myeloid leukemia. Molecular Therapy Nucleic Acids (2015) 4: e240.
           1 file(s)  416 downloads

          2015

          July 1, 2015

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          Remant Bahadur KC, C. Kucharski, H. Uludağ. Additive nanocomplexes of cationic lipopolymers for improved non-viral gene delivery to mesenchymal stem cells. J. Mat. Chem. (2015) 3: 3972-3982.
           1 file(s)  384 downloads

          2015

          May 12, 2015

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          D. Meneksedağ-Erol, T. Tian, H. Uludağ. Probing the effect of miRNA on siRNA – PEI polyplexes. J. Phys. Chem. B (2015) 119: 5475-5486.
           1 file(s)  588 downloads

          2015

          May 2, 2015

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          M.B. Parmar, H.M. Aliabadi, P. Mahdipoor, C. Kucharski, R. Maranchuk, J.C. Hugh, H. Uludağ. Targeting cell cycle proteins in breast cancer cells with siRNA by using lipid-substituted polyethylenimines. Frontiers in Biotechnology & Bioengineering (2015) 3:14.
           1 file(s)  414 downloads

          2015

          May 2, 2015

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          M. Parmar, H. Uludag. Cell Cycle Regulation as a Target for RNAi Mediated Cancer Therapy. In Nanomedicines: Design, Delivery and Detection, M. Braddock (Ed.) (2015) in press.
           1 file(s)  6 downloads

          2015

          May 2, 2015

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          Remant K.C., H. Uludag. PEI and Its Derivatives in Gene Delivery. In Polymers and Nanomaterials in Gene Delivery. R. Narain (Ed). Woodhead Publishing Limited, Cambridge, UK (2015) in press.
           1 file(s)  10 downloads

          2015

          May 2, 2015

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          H.M. Aliabadi, H. Uludag. Nanoparticle Carriers to Overcome Biological Barriers Barriers to siRNA Delivery. In Nanomedicines: Design, Delivery and Detection, M. Braddock (Ed.) (2015) in press.
           1 file(s)  7 downloads

          2015

          May 2, 2015

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            Title
            A. Falamarzian, H.M. Aliabadi, 0. Molavi, J.M. Seubert, R. Lai, H. Uludag, A. Lavasanifar. Effective down-regulation of signal transducer and activator of transcription 3 (STAT3) by polyplexes of siRNA and lipid-substituted polyethyleneimine for sensitization of breast tumor cells to conventional chemotherapy. J. Biomed. Mat. Res. A. (2014) 102: 3216-3228.
             1 file(s)  322 downloads

            2014

            April 4, 2015

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            L Rose, C. Kucharski, P. Mandipoor, H. Uludag. Pharmacokinetics and transgene expression by polytheylenimine-based pDNA complexes after in vivo gene delivery. Biomaterials Science (2014) 2: 833-842.
             1 file(s)  362 downloads

            2014

            April 4, 2015

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            H. Kaur, H. Uludag, T. El-Bialy. Effect of non-viral plasmid delivered basic Fibroblast Growth Factor and Low Intensity Pulsed Ultrasound on mandibular condylar growth: a preliminary study. BioMed Research Int. (2014) 2014:426710.
             1 file(s)  276 downloads

            2014

            April 4, 2015

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            H. Gul-Uludag, J. Valencia-Serna, C. Kucharski, L.A. Marquez-Curtis, X. Jiang, L. Larratt, A. Janowska-Wieczorek, H. Uludag. Nanoparticle-mediated silencing of CD44 receptor in CD34+ acute myeloid leukemia blasts. Leukemia Research (2014) in press.
             1 file(s)  328 downloads

            2014

            April 4, 2015

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            B. Sahin, J. Fife, M. Parmar, J. Valencia-Serna, H. Gul-Uluda, X. Jiang, M. Weinfeld A. Lavasanifar, H. Uludag. Polymeric carriers for siRNA delivery in cutaneous T-cell lymphoma cells. Biomaterials (2014) 35: 9382-9394.
             1 file(s)  328 downloads

            2014

            April 4, 2015

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            D. Meneksedag-Erol, T. Tang, H. Uludag. Molecular modelling of polynucleotide complexes. Biomaterials (2014) 35: 7068-7076.
             1 file(s)  395 downloads

            2014

            May 2, 2015

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            H. Uludag. Grand Challanges in Biomaterials Science. Frontiers in Bioengineering and Biotechnology (2014) 2: 43.
             1 file(s)  278 downloads

            2014

            April 4, 2015

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            J. Valencia-Serna, B. Landry, X. Jiang, H. Uludag. Potential of siRNA Therapy in Chronic Myeloid Leukemia. In Intracellular Drug Delivery: Fundamentals and Applications, Volume II, A. Prokop, Y. Iwasaki, A. Harada (Eds) Springer (2014), pp 435-473.
             1 file(s)  330 downloads

            2014

            April 4, 2015

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            D. Meneksedag-Erol, C. Sun, T. Tang, H. Uludag. Molecular Dynamics Simulations of Polyplexes and Lipoplexes Employed in Gene Delivery. In Intracellular Drug Delivery: Fundamentals and Applications, Volume II, A. Prokop, Y. Iwasaki, A. Harada (Eds) Springer (2014), pp 277-312.
             1 file(s)  368 downloads

            2014

            April 4, 2015

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              Title
              M. Abbasi, A. Lavasanifar, H. Uludag. Recent attempts at RNAi based downregulation of P-glycoprotein in reversing multidrug resistance in cancer. Medicinal Research Reviews (2013) 33: 33-53.
               1 file(s)  518 downloads

              2013

              April 4, 2015

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              C. Sun, T. Tang, H. Uludag. A molecular dynamics simulation study on the effect of lipid substitution on polyethylenimine mediated siRNA complexation. Biomaterials (2013) 34: 2822-2833.
               1 file(s)  279 downloads

              2013

              April 4, 2015

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              L Rose, R. Fitzsimmons, P. Lee, R. Krawetz, D.E. Rancourt, H. Uludag. Effect of bFGF in mouse embryonic stem cell culture and osteogenic differentiation. Journal of Tissue Engineering & Regenerative Medicine (2013) 7: 371-382.
               1 file(s)  270 downloads

              2013

              April 4, 2015

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              J. Valencia-Serna, H. Gul-Uludag, P. Mandipoor, J. Jiang, H. Uludag. Investigating siRNA delivery to chronic myeloid leukemia K562 cells with lipophilic polymers for therapeutic BCR-ABL down-regulation. Journal of Controlled Release (2013) 172: 495-503.
               1 file(s)  345 downloads

              2013

              April 4, 2015

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              B. Dube, L. Rose, K. Sawant, H. Uludag. Cholic acid modified 2 kDa PEI as efficient transfection agents. Biotechnology Progress (2013) 29: 1337-1341.
               1 file(s)  282 downloads

              2013

              April 4, 2015

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              Y. Wang, N.Z. Mostafa, C.Y.M. Hsu, L Rose, C. Kucharki, J. Yan, H. Jiang, H. Uludag. Modification of human BMSC with nanoparticles of polymeric biomaterials and plasmid DNA for BMP-2 secretion. Journal of Surgical Research (2013) 183: 8-17.
               1 file(s)  316 downloads

              2013

              April 4, 2015

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              H.M. Aliabadi, P. Mandipoor, H. Uludag. Polymeric delivery of siRNA for dual silencing of Mcl-1 and P-glycoprotein and apoptosis induction in drug-resistant human breast cancer cells. Cancer Gene Therapy (2013) 20: 169-177.
               1 file(s)  334 downloads

              2013

              April 4, 2015

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              L Rose, H.M. Aliabadi, H. Uludag. Gelatin coating to stabilize the transfection ability of nucleic acid polyplexes. Acta Biomaterialia (2013) 7: 7429-7438.
               1 file(s)  289 downloads

              2013

              April 4, 2015

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              L Rose, H. Uludag. Realizing the potential of gene-based molecular therapies in bone repair.Journal of Bone & Mineral Research (2013) 28: 2245-2262.
               1 file(s)  358 downloads

              2013

              April 4, 2015

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              H.M. Aliabadi, P. Mandipoor, R. Marenchuk, J. Hugh, H. Uludag. Combinational siRNA therapy in drug-sensitive and drug-resistant breast cancer cells. Journal of Controlled Release (2013) 172: 219-228.
               1 file(s)  355 downloads

              2013

              April 4, 2015

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                Title
                C. Sun, T. Tang, H. Uludag. Probing the effects of lipid substitution on polycation mediated DNA aggregation: a molecular dynamics simulations study. Biomacromolecules (2012) 13: 2982-2988.
                 1 file(s)  341 downloads

                2012

                April 4, 2015

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                B. Landry, H.M. Aliabadi, A. Samuel, H. Giil-Uludag, X. Jiang, 0. Kutsch, H. Uludag. Effective non-viral delivery of siRNA to acute myeloid leukemia cells with lipid-substituted polyethylenimines. PLOS One (2012) 7: e44197
                 1 file(s)  356 downloads

                2012

                April 4, 2015

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                C. Chen, H. Uludag, Z. Wang, A. Rezansoff, H. Jiang. Macrophages inhibit migration, metabolic activity and osteogenic differentiation of human mesenchymal stem cells in vitro. Cells, Tissue, Organs (2012) 195: 473-483.(no link to paper)
                 1 file(s)  290 downloads

                2012

                April 4, 2015

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                C. Chen, H. Uludag, Z. Wang, H. Jiang. Noggin suppression decreases BMP-2 induced osteogenesis of human bone marrow mesenchymal stem cells in vitro. J. Cell. Biochem. (2012) 113: 3672-3680.
                 1 file(s)  327 downloads

                2012

                April 4, 2015

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                C.Y.M Hsu, H. Uludag. Nucleic-acid based gene therapeutics: delivery challenges and modular design of gene carriers and expression cassettes to overcome intracellular barriers to sustained targeted expression. J. Drug Targeting (2012) 20: 301-328.
                 1 file(s)  356 downloads

                2012

                April 4, 2015

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                A. Falamarzian, X-B. Xiong, H. Uludag, A. Lavasanifar. Polymeric micelles for targeted siRNA delviery. J. Drug Del. Sci. Technol. (2012) 22: 43-54.
                 1 file(s)  350 downloads

                2012

                April 4, 2015

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                H.M. Aliabadi, B. Landry, C. Sun, T. Tang, H. Uludag. Supramolecular in functional siRNA delivery: where do we stand? Biomaterials (2012) 33: 2546-69.
                 1 file(s)  361 downloads

                2012

                April 4, 2015

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                C. Sun, T. Tang, H. Uludag. Molecular dynamics simulations of complexation of DNA with 2 kDa PEI reveals profound effects of architecture on complexation. J. Phys. Chem B (2012) 116: 2405-2413.
                 1 file(s)  308 downloads

                2012

                April 4, 2015

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                C.Y.M. Hsu, H. Uludag. A simple and rapid non-viral approach to efficiently transfect primary tissue derived cells using polyethylenimine. Nature Protocols (2012) 7: 935-945.
                 1 file(s)  396 downloads

                2012

                April 4, 2015

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                R.E.B. Fitzsimmons, H. Uludag. Specific effects of PEGylation on gene delivery efficacy of PEI: interplay between PEG substitution and N/P ratio. Acta Biomaterilia (2012) 8: 3941-3955.
                 1 file(s)  353 downloads

                2012

                April 4, 2015

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                H. Yogasundaram, M.S. Bahniuk, HD. Singh, H.M. Aliabadi, H. Uludag, L.D Unsworth. BSA nanoparticles for siRNA delivery: effect of nanoparticle coating on plasma protein adsorption and in vitro siRNA delivery. Int. J. Biomat. (2012) ID 584060.
                 1 file(s)  333 downloads

                2012

                April 4, 2015

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                H.M. Aliabadi, B. Landry, C.Y.M Hsu P. Mandipoor, H. Uludag. Down-regulation of Breast Cancer Resistance Protein (BCRP) by siRNA delivery using lipid-substituted aliphatic polymers. Eur. J. Pharmaceutics and Biopharmaceutics (2012) 81: 33-42.
                 1 file(s)  360 downloads

                2012

                April 4, 2015

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                G. Wang, N.Z. Mostafa, V. Incani, C. Kucharski, H. Uludag. Bisphosphonate-decorated lipid nanoparticles designed as drug carriers for bone diseases. J. Biomed. Mat. Res. (2012) 100A: 684-695.
                 1 file(s)  319 downloads

                2012

                April 4, 2015

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                C.Y.M. Hsu, H. Uludag. Cellular uptake pathways of lipid-modified cationic polymers in gene delivery to primary cells. Biomaterials (2012) 33: 7834-7848.
                 1 file(s)  312 downloads

                2012

                April 4, 2015

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                L Rose, C. Kucharski, H. Uludag. Protein expression following non-viral delivery of plasmid DNA coding for bFGF and BMP-2 in a rat ectopic model. Biomaterials (2012) 33: 3363-3374.
                 1 file(s)  341 downloads

                2012

                April 4, 2015

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                N.Z. Mostafa, R. Fitzsimmons, P.W. Major, A. Adesida, N. Jomha, H. Jiang, H. Uludag Osteogenic differentiation of human mesenchymal stem cells with dexamethasone, vitamin D3, basic Fibroblast Growth Factor and Bone Morphogenetic Protein-2. Connective Tissue Research (2012) 53: 117-131.
                 1 file(s)  376 downloads

                2012

                April 4, 2015

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                  Title
                  H.M. Aliabadi, B. Landry, P. Mandipoor, H. Uludag. Induction of apoptosis by surviving silencing through siRNA delivery in a human breast cancer cell line. Molecular Pharmaceutics (2011) 8: 1821-1830.
                   1 file(s)  331 downloads

                  2011

                  April 4, 2015

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                  D. Zhang, F. Chu, Y. Yang, L. Xia, D. Zeng, X. Zhang, H. Uludag, Y. Q_ian, X. Jiang. Orthodontic tooth movement in alveolar cleft repaired with a tissue engineering bone: an experimental study in dogs. Tissue Engineering (2011) 17: 1313-1325.
                   1 file(s)  374 downloads

                  2011

                  April 4, 2015

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                  L. Zhi, C. Chen, X. Pang, H. Uludag, H. Jiang. Synergistic effect of rhBMP-7 and osteogenic differentiation medium on human bone marrow-derived mesenchymal stem sells in vitro. Int. Orthopeadics (2011) 35:1889-1895.
                   1 file(s)  247 downloads

                  2011

                  May 2, 2015

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                  M. Abbasi, H.M. Aliabadi, E.H. Moase, A. Lavasanifar, K. Kaur, R. Lai, C. Doillon, H. Uludag. siRNA mediated down-regulation of P-glycoprotein in a xenograft tumor model in NOD-SCID mice. Pharm. Res. (2011) 28: 2516-2529.
                   1 file(s)  381 downloads

                  2011

                  April 4, 2015

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                  G. Wang, M.E. Babadagli, H. Uludag. Bisphosphonate-derivatized liposomes to control drug release from collagen/hydroxyapatite scaffolds. Mol. Pharmaceutics (2011) 8:1025-1034.
                   1 file(s)  408 downloads

                  2011

                  May 2, 2015

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                  N.Z. Mostafa, H. Uludag, M. Varkey, D.N. Dederich, M.R. Doschak, T.H. El-Bialy. In vitro osteogenic induction of human gingival fibroblasts for bone regeneration. Open Dental Journal (2011) 5:139-145.
                   1 file(s)  373 downloads

                  2011

                  May 2, 2015

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                  A. Alshamsan, S. Hamdy, I. Samuel, A. Haddadi, A.O.S. El-Kadi, A. Lavasanifar, H. Uludag. STAT3 knockdown in BIG melanoma by siRNA lipopolyplexes induces bystander immune response in vitro and in vivo. Translational Oncology (2011) 4: 178-188.
                   1 file(s)  338 downloads

                  2011

                  April 4, 2015

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                  H.M. Aliabadi, B. Landry, R. Bahadur K.C., A. Neamnark, 0. Suwantong, H. Uluda. Impact of lipid-substitution on assembly and delivery of siRNA by cationic polymers. Macromol. Biosci. (2011) 11: 662-672.
                   1 file(s)  335 downloads

                  2011

                  April 4, 2015

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                  C. Hsu, M. Hendzel, H. Uludag. Improved transfection efficiency of an aliphatic lipid substituted 2 kDa polyethylenimine is attributed to enhanced nuclear association and uptake in rat bone marrow stromal cells. 1. Gene Med. (2011) 13: 46-59.
                   1 file(s)  294 downloads

                  2011

                  April 4, 2015

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                  C. Sun, J.E. Cuervo, T. Tang, H. Uludag. Molecular dynamics simulations of DNA/PEI complexes: Effect of PEI branching and protonation ratio. Biophys. l (2011) 100: 2754-2763.
                   1 file(s)  294 downloads

                  2011

                  April 4, 2015

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                  Remant K.C., H. Uludag. A comparative evaluation of disulfide-linked and hydrophobically-modified PEI for plasmid delivery. I. Biomat. Sci. Poly. Ed. (2011) 22: 873-892.
                   1 file(s)  341 downloads

                  2011

                  April 4, 2015

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                  Remant Bahadur K.C., B. Landry, H.M. Aliabadi, et al. Lipid-substitution on low molecular weight (0.6 – 2.0 kDa) PEI leads to higher zeta-potential with plasmid DNA and enhances transgene expression. Acta Biomaterialia (2011) 7: 2209-2217.
                   1 file(s)  264 downloads

                  2011

                  April 4, 2015

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                  C. Sun, T. Tang, H. Uludag. Molecular dynamics simulations of PEI mediated DNA aggregation. Biomacromolecules (2011) 12: 3698-3707.
                   1 file(s)  435 downloads

                  2011

                  July 14, 2016

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                    H.M. Aliabadi, B. Landry, P. Mahdipoor, H. Uludag. Induction of apoptosis by surviving silencing through siRNA delivery in a human breast cancer cell line. Molecular Pharmaceutics (2011) 8: 1821-1830.


                    C. Sun, T. Tang, H. Uludag. Molecular dynamics simulations of PEI mediated DNA aggregation. Biomacromolecules (2011) 12: 3698-3707.


                    N.Z. Mostafa, H. Uluda, M. Varkey, D.N. Dederich, M.R. Doschak, T.H. El-Bialy. In vitro osteogenic induction of human gingival fibroblasts for bone regeneration. Open Dental Journal (2011) 5:139-145.


                    G. Wang, M.E. Babadali, H. Uludag. Bisphosphonate-derivatized liposomes to control drug release from collagen/hydroxyapatite scaffolds. Mol. Pharmaceutics (2011) 8: 1025-1034.


                    M. Abbasi, H.M. Aliabadi, E.H. Moase, A. Lavasanifar, K. Kaur, R. Lai, C. Doillon, H. Uludag. siRNA mediated down-regulation of P-glycoprotein in a xenograft tumor model in NOD-SCID mice. Pharmaceutical Research (2011) 28: 2516-2529.


                    C. Sun, J.E. Cuervo, T. Tang, H. Uludag. Molecular dynamics simulations of DNA/PEI complexes: Effect of PEI branching and protonation ratio. Biophys. J (2011) 100: 2754-2763.


                    A. Alshamsan, S. Hamdy, J. Samuel, A. Haddadi, A.O.S. El-Kadi, A. Lavasanifar, H. Uludag. STAT3 knockdown in B16 melanoma by siRNA lipopolyplexes induces bystander immune response in vitro and in vivo. Translational Oncology (2011) 4: 178-188.


                    Remant Bahadur K.C., B. Landry, H.M. Aliabadi, A. Lavasanifar, H. Uluda, Lipid-substitution on low molecular weight (0.6 – 2.0 kDa) polyethylenimine leads to higher zeta-potential with plasmid DNA and enhances transgene expression. Acta Biomaterialia (2011) 7: 2209-2217.


                    D. Zhang, F. Chu, Y. Yang, L. Xia, D. Zeng, X. Zhang, H. Uludag, Y. Qian, X. Jiang. Orthodontic tooth movement in alveolar cleft repaired with a tissue engineering bone: an experimental study in dogs. Tissue Engineering (2011) 17: 1313-1325.


                    H.M. Aliabadi, B. Landry, R. Bahadur K.C., A. Neamnark, O. Suwantong, H. Uluda. Impact of lipid-substitution on assembly and delivery of siRNA by cationic polymers. Macromol. Biosci. (2011) 11: 662-672.


                    C. Hsu, M. Hendzel, H. Uludag. Improved transfection efficiency of an aliphatic lipid substituted 2 kDa polyethylenimine is attributed to enhanced nuclear association and uptake in rat bone marrow stromal cells. J. Gene Med. (2011) 13: 46-59.


                    Remant K.C., H. Uludag. A comparative evaluation of disulfide-linked and hydrophobically-modified PEI for plasmid delivery. J. Biomat. Sci. Poly. Ed. (2011) 22: 873-892.


                    A. Alshamsan, A. Haddadi, S. Hamdy, J. Samuel, A.O.S. El-Kadi, H. Uluda, A. Lavasanifar. STAT3 silencing in dendritic cells by siRNA siRNA polyplexes encapsulated in PLGA nanoparticles for the modulation of anticancer immune response. Molecular Pharmaceutics (2010) 7: 1643-1654.


                    C.E. Taghavi, K-B. Lee, W. He, G. Keorochana, S.S. Murray, E.J. Brochmann, H. Uluda, K. Behnam, J.C. Wang. Bone morphogenetic protein binding peptide mechanism and enhancement of Osteogenic Protein-1 induced bone healing. Spine (2010) 35: 2049-2056.


                    H.D Singh, G. Wang, H. Uluda, L.D. Unsworth. Poly-L-Lysine coated albumin nanoparticles: stability, mechanism for increasing in vitro enzymatic resilience, and siRNA release characteristics. Acta Biomaterialia (2010) 6: 4277–4284.


                    K.H. Bhandari, M. Newa, H. Uluda, M.R. Doschak. Synthesis, characterization and in vitro evaluation of a bone targeting delivery system for salmon calcitonin. Int J Pharmaceut (2010) 394: 26-34.


                    K. Utsuno, H. Uluda. Thermodynamics of PEI-DNA binding and DNA condensation. Biophys. J (2010) 99: 201-207.


                    X-B. Xiong, H. Uluda, A. Lavasanifar. Virus-mimetic polymeric micelles for targeted siRNA delivery to human cancer cells. Biomaterials (2010) 31: 5886-5893.


                    S. Zhang, C. Kucharski, M.R. Doschak, W. Sebald, H. Uluda. Polyethylenimine-PEG coated albumin nanoparticles for BMP-2 Delivery. Biomaterials (2010) 31: 952-63.


                    T. El-Bialy, H. Uludag, N. Jomha, S. Badylak. In vivo ultrasound assisted tissue engineered mandibular condyle: A pilot study in rabbits. Tissue Engineering (2010) 16: 1315-1323.


                    M. Abbasi, A. Lavasanifar, L. Berthiaume, M. Weinfeld, H. Uluda. Cationic polymer mediated siRNA delivery for P-glycoprotein (P-gp) down-regulation in tumor cells. Cancer (2010) 116: 5544-5554.


                    G. Wang, C. Kucharski, X. Lin, H. Uluda. Bisphosphonate-coated BSA nanoparticles lacks bone targeting after systemic administration. J. Drug Target. (2010) 18: 611-626.


                    S. Wang, Z. Zhang, L. Xia, J. Zhao, X. Sun, X. Zhang, D. Ye, H. Uluda, X. Jiang. Systematic evaluation of a tissue-engineered bone for maxillary sinus augmentation in large animal canine model. Bone (2010) 46: 91-100.


                    A. Alshamsan, J. Samuel, H. Uluda, A.O.S. El-Kadi, A. Lavasanifar. The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine. Biomaterials (2010) 31: 1420-1428.


                    V. Incani, A. Lavasanifar A, H. Uluda. Hydrophobic modification of cationic polymers on route to superior gene carriers. Soft Matter (2010) 6: 2124–2138.


                    A. Naemnark, O. Suwantang, Remant Bahadur K.C., Charlie Y.M. Hsu, P. Supaphol, H. Uluda. Aliphatic lipid substitution on 2 kDa-polyethylenimine improves plasmid delivery and transgene expression. Mol. Pharmaceut. (2009) 6: 1798-1815.


                    S. Zhang, M. Doschak, H. Uluda. Pharmacokinetics and bone formation by BMP-2 entrapped in polyethylenimine-coated albumin nanoparticles. Biomaterials (2009) 30: 5143-5155.


                    N.Z. Mostafa, H. Uluda, D.N. Dederich, M. Doschak, T. El-Bialy. Anabolic effects of low intensity pulsed ultrasound on gingival fibroblasts. Arch. Oral Biol. (2009) 54: 743-748.


                    V. Incani, X. Lin, A. Lavasanifar, H. Uluda. Relationship between the extent of lipid substitution on Poly(L-Lysine) and DNA delivery efficiency. Appl. Mat. Interf. (2009) 1: 841-848.


                    B.A. Clements, C.Y.M. Hsu, C. Kucharski, X. Lin, L. Rose, H. Uluda. Non-viral delivery of basic Fibroblast Growth Factor (bFGF) gene to bone marrow stromal cells. Clin. Orthop. Rel. Res. (2009) 467: 3129-3137.


                    R.B. Jalili, F. Forouzandeh, A. Moeenrezakhanlou, G.R. Rayat, R.V. Rajotte, H. Uluda, A. Ghahary. Mouse pancreatic islets are resistant to Indoleamine 2,3 Dioxygenase-induced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function. Am. J. Pathol. (2009) 174: 196-205.


                    M.R. Doschak, C.M Kucharski, J.E.I. Wright, R.F. Zernicke, H. Uluda, Improved bone delivery of osteoprotegerin by bisphosphonate conjugation in a rat osteoarthritis model. Mol. Pharmaceut. (2009) 6: 634-640.


                    A. Alshamsan, A. Haddadi, V. Incani, J. Samuel, A. Lavasanifar, H. Uluda. Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine.. Mol. Pharmaceut. (2009) 6: 121-133.


                    X.B. Xiong, H. Uluda, A. Lavasanifar. Biodegradable amphiphilic poly(ethylene oxide)-block-polyesters with grafted polyamines as supramolecular nanocarriers for efficient siRNA delivery. Biomaterials (2009) 30: 242-253.


                    S. Zhang, H. UludaG, Nanoparticulate systems for growth factor delivery. Pharm. Res. (2009) 26: 1561-1580.


                    G. Wang, K. Siggers, S. Zhang, H. Jiang, Z. Xu, R.F. Zernicke, J. Matyas, H. Uluda. Preparation of BMP-2 containing bovine serum albumin (BSA) nanoparticles stabilized by polymer coating. Pharm. Res. (2008) 25: 2896-2909.


                    X.-B. Xiong, A. Mahmud, H. Uludag, A. Lavasanifar. Multifunctional polymeric micelles for enhanced intracellular delivery of doxorubicin to metastatic cancer cells. Pharm. Res. (2008) 25: 2555-2566.


                    W.T Ang, C. Yu, J. Chen, T. El-Bialy, M. Doschak, H. Uludag, Y. Tsui. System-on-chip ultrasonic transducer for dental tissue formation and stem cell growth and differentiation. Proc. IEEE Symposium on Circuits and Systems (2008) 1818-1821.


                    S. Zhang, G. Wang, X. Lin, H. Jennissen, M. Chatzinikolaidou, M. Laub, H. Uludag. Polyethylenimine-coated albumin nanoparticles for BMP-2 Delivery. Biotech. Prog. (2008) 24: 945-956.


                    M. Abbasi, H. Uludag, C. Hsu, V. Incani, A. Jeffery. Further investigation of lipid-substituted poly(L-Lysine) polymers for transfection of human CRL fibroblasts. Biomacromol. (2008) 9, 1618-1630.


                    C. Hsu, H. Uludag. Effect of size and topology of DNA molecules on intracellular delivery with non-viral gene carriers. BMC Biotech. (2008) 8: 23.


                    B.A. Clements, V. Incani, C. Kucharski, B. Ritchie, A. Lavasanifar, H. Uludag. A comparative evaluation of poly-L-lysine-palmitic acid and LipofectamineTM 2000 for plasmid delivery to bone marrow stromal cells. Biomat. (2007) 28: 4693-4704.


                    S. Zhang, J.E.I. Wright, N. Ozber, H. Uludag. Interactions of cationic polymers and their bisphosphonate derivatives with hydroxyapatite. Macromol. Biosci. (2007) 7: 656-670.


                    L.-L. Farrell, J. Pepin, C. Kucharski, X. Lin, Z. Xu, H. Uludag. A comparison of the effectiveness of cationic polymers poly-L-lysine (PLL) and polyethyleneimine (PEI) for non-viral delivery of plasmid DNA to bone marrow stromal cells. Eur. J. Pharmaceut. Biopharmaceut. (2007) 65: 388-397.


                    X.-B. Xiong, A. Mahmud, H. Uludag, A. Lavasanifar. Conjugation of arginine-glycine-aspartic acid peptides to poly(ethylene-oxide)-b-poly(-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells. Biomacromol. (2007) 8: 874-884.


                    M. Abbasi, H. Uludag, V. Incani, C. Olson, X. Lin, D. Rutkowski, A. Ghahary, M. Weinfeld. Palmitic acid-modified poly-l-lysine for non-viral delivery of plasmid DNA to skin fibroblasts. Biomacromol. (2007) 8: 1059-1063.


                    M. Varkey, C. Kucharski, M.R. Doschak, S.R. Winn, E.J. Brochmann, S. Murray, J.R. Matyas, R.F. Zernicke, H. Uludag. Osteogenic response of bone marrow stromal cells form normal and ovariectomized rats treated with low dose of bFGF. Tissue Eng. (2007) 13: 809-817.


                    V. Incani, E. Tunis, B.A. Clements, C. Olson, C. Kucharski, A. Lavasanifar, H. Uludag. Palmitic acid substitution on cationic polymers for effective delivery of plasmid DNA to bone marrow stromal cells. J. Biomed. Mat. Res. (2007) 81: 493-504.


                    G. Wang, H. Uludag. Recent developments in nanoparticle-based drug delivery and targeting systems. Exp. Op. Drug Del. (2008) 5: 499-515.


                    S. Zhang, G. Bansal, H. Uludag. ‘Magic Bullets’ for bone diseases: progress in rational design of bone therapeutics based on bisphosphonate targeting. Chem. Soc. Rev. (2007) 36: 507-531.


                    X. Jiang, J. Bai, S.A. Gittens, W. Sebald, H. Uludag. Growth of Bone Marrow Stromal Cells on RGD-grafted thermoreversible (NiPAM) polymers. Mat. Sci. Eng. (2006) 37: 462-468.


                    B. Açan-Clemens, J. Bai, C. Kucharski, L.-L. Farrell, A. Lavasanifar, B. Ritchie, A. Ghahary, H. Uludag. RGD-conjugation to polyethyleneimine does not improve DNA delivery to bone marrow stromal cells. Biomacromol. (2006) 7: 1481-1488.


                    M. Varkey, C. Kucharski, T. Haque, W. Sebald, H. Uludag. In vitro osteogenic response of rat bone marrow cells to bFGF and BMP-2 treatments. Clin. Orthop. Rel. Res. (2006) 443: 113-123.


                    J.E.I. Wright, S.A. Gittens, G. Bansal, P.I. Kitov, D. Sindrey, C. Kucharski, H. Uludag. A comparison of mineral affinity of bisphosphonate-protein conjugates constructed with disulfide and thioether linkages. Biomaterials (2006) 27: 769-784.